That happen to me too,but it was the Galloaway mission. The Door to the second room wouldnt open and I tried everything to get it to open. I used all the weapons I had but nothing worked. I went outside and beat up the orderlys out there and just passed out..when I woke up I went inside the Asylum and the door had the blue marker by it.
So I would just stay there all day and pass out and go into the place again.
